Around £22,000 worth of computers and televisions has been stolen from Shebbear College.
Police said computer equipment, including laptops, notebooks, televisions and photographic items were taken from the college in Beaworthy at some point between 6.30pm on Monday and 7am on Tuesday.
Extensive damage was also caused to the several buildings in and around the college as the burglars attempted to gain access to the school.
Police estimate the value of the stolen items to be around £22,000 and are appealing to anyone with information to come forward.
Anyone with information is asked to contact police on 101, or Crimestoppers in confidence on 0800 555 111, quoting reference CT/13/70.