Jamie Overton suffered a blow on the thigh while batting for England under-19s in the fourth one-day international against South Africa in Stellenbosch yesterday.
It meant he was only able to bowl one over as South Africa wrapped up a six-wicket win under the Duckworth-Lewis Method to go 4-0 up in the five-match series.
Overton, the North Devon and Somerset pace bowler, had made 38 and 48 in his previous two appearances on the tour.
Hampered by the injury, he contributed six to England's 205 for eight.
Overton opened the bowling in South Africa's reply and sent down a maiden but, grimacing between each ball, he was unable to continue.
Two rain breaks left the home side with an amended target which they reached with an over to spare.
John Abrahams, the England manager, said he hoped Overton would be fit to play in the last match at Cape Town tomorrow.
See tomorrow's North Devon Journal for a special report on Jamie Overton in South Africa.