Woolacombe and Mortehoe 12 Lynton and Lynmouth 0: After last week's 13-1 win over Northam Lions, Woolacombe have plundered 25 goals in two games.
Marc Churchill, a defender, was the chief beneficiary, firing a second-half hat-trick for his first goals since joining from Wrey Arms.
It was a tough afternoon for Lynton as Richard Badham dislocated a finger in the first five minutes and was driven to hospital by substitute Mark Bithell.
Andy Woodman and Chay Isaac scored two each, Matt Lambert, Andy Ley and Paddy Weathers claimed the singles and Dan Wright hit two, including one with his first touch after stepping off the bench.
Braunton 1 Barnstaple FC 7: Andy Vernon made amends for an own goal when he went forward at a set piece to score at the right end too.
It was a comfortable win for Barnstaple as Connor Nash and Maurice Charley, with two goals each, Keith McClure and Sam Phillips booked a home tie against the winners of Landkey Town and Halwill in the area quarter-finals.
Equalizers 4 High Bickington 2: Substitute Luke Phillips scored with a volley from the edge of the box to seal the win for Equalizers in stoppage time.
High Bickington took an early lead through Ben Prosser before Mathew Mitchell fired the equaliser past stand-in goalkeeper Darren Avery.
Two headed goals from Matt Hawkins put the Barnstaple club in control and they held out to book a meeting with Hartland in the next round after Tom Sanders pulled one back.
Clovelly 1 Torridgeside 2: Torridgeside battled back to set up a meeting with Woolacombe and Mortehoe after falling behind to a long-range strike from Nick Brazier.
Sam Pett pounced for the equaliser and the visitors' endeavour was rewarded with an own goal to clinch the game.
Hartland 6 Fremington 3: Adam Symonds scored his first two goals for Hartland since signing from Woolsery. Richard Davey, Joe Dakin, Jack Coleman and an own goal sent Hartland through after Fremmy's Gary Grant, Luke Ovey and Mark Sanders had made it 3-3.